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* Acyl-CoA-binding protein signature *
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Acyl-CoA-binding protein  (ACBP) is a small (10 Kd) protein that binds medium-
and long-chain  acyl-CoA esters with very high affinity and may function as an
intracellular carrier  of  acyl-CoA  esters  [1].    ACBP  is  also  known  as
diazepam  binding inhibitor (DBI) or endozepine (EP) because of its ability to
displace diazepam  from  the  benzodiazepine (BZD) recognition site located on
the GABA type A receptor. It is therefore possible that this protein also acts
as a neuropeptide to modulate the action of the GABA receptor [2].

ACBP is a highly conserved  protein  of about 90 residues that has been so far
found in  vertebrates,  insects  and  yeast.  ACBP  is  also related to the N-
terminal section of a probable transmembrane protein of unknown function which
has been found in mammals.

As a signature pattern we selected  the region  that corresponds to residue 19
to 37 in mammalian ACBP.

-Consensus pattern: P-[STA]-x-[DEN]-x-[LIVM](2)-x-[LIVMFY]-Y-[GSTA]-x-[FY]-K-
                    Q-A-[STA]-x-G
-Sequences known to belong to this class detected by the pattern: ALL.
-Other sequence(s) detected in SWISS-PROT: NONE.
-Last update: October 1993 / First entry.

[ 1] Rose T.M., Schultz E.R., Todaro G.J.
     Proc. Natl. Acad. Sci. U.S.A. 89:11287-11291(1992).
[ 2] Costa E., Guidotti A.
     Life Sci. 49:325-344(1991).