********************************************************
* Pathogenesis-related proteins BetvI family signature *
********************************************************

A number of plant proteins, which  all seem to be involved in pathogen defense
response, are structurally related [1,2,3]. These proteins are:

 - Asparagus wound-induced protein AoPR1.
 - Kidney bean pathogenesis-related proteins 1 and 2.
 - Parsley pathogenesis-related proteins PR1-1 and PR1-3.
 - Pea disease resistance response proteins pI49 and pI176.
 - Potato pathogenesis-related proteins STH-2 and STH-21.
 - Soybean stress-induced protein SAM22.
 - Bet  v  I,  the major pollen allergen from white birch. Bet v I is the main
   cause of type I allergic reactions in Europe, North America and USSR.

These proteins  are  thought  to be intracellularly located. They contain from
155 to  160  amino  acid  residues.  As  a  signature  pattern,  we selected a
conserved region located in the third quarter of these proteins.

-Consensus pattern: G-x(2)-[LIVMF]-x(4)-E-x(2)-[STN]-x(8,9)-[ND]-G-G-[CS]-
                    x(2)-K-x(4)-[FY]
-Sequences known to belong to this class detected by the pattern: ALL.
-Other sequence(s) detected in SWISS-PROT: NONE.
-Last update: June 1994 / Pattern and text revised.

[ 1] Breiteneder H., Pettenburger K., Bito A., Valenta R., Kraft D.,
     Rumpold H., Scheiner O., Breitenbach M.
     EMBO J. 8:1935-1938(1989).
[ 2] Crowell D., John M.E., Russell D., Amasino R.M.
     Plant Mol. Biol. 18:459-466(1992).
[ 3] Warner S.A.J., Scott R., Draper J.
     Plant Mol. Biol. 19:555-561(1992).
