The scientific study of crystals. In 1912, it was found that the shape and size of the unit cell of a crystal can be discovered by X-rays, thus opening up an entirely new way of `seeing' atoms. This means of determining the atomic patterns in a crystal is known as X-ray diffraction. It has been shown that even purified biomolecules, such as proteins and DNA, can form crystals, and such compounds may now be studied by the same method. Another field of application of X-ray analysis lies in the study of metals and alloys. Crystallography is also of use to the geologist studying rocks and soils. Many materials were not even suspected of being crystals until they were examined by X-ray crystallography. By this method it has been found that many substances have unit cells or boxes which are exact cubes, for example ordinary table salt (sodium chloride).