Basal metabolic rate, (BMR) The amount of energy needed by an animal just to stay alive. It is measured when the animal is awake but resting, and includes the energy required to keep the heart beating, sustain breathing, repair tissues, and keep the brain and nerves functioning. Measuring the animal's consumption of oxygen gives an accurate value for BMR, because oxygen is needed to release energy from food. A cruder measure of BMR estimates the amount of heat given off, some heat being released when food is used up. BMR varies from one species to another, and from males to females. In humans, it is highest in children and declines with age. Disease, including mental illness, can make it rise or fall. Hormones from the thyroid gland control the BMR.