AZT or retrovir, or zidovudine Trademark for azidothymidine, an antiviral drug used in the treatment of AIDS. Developed in the mid-1980s and approved for use by 1987, it is not a cure for AIDS, but is effective in suppressing the causative virus (HIV) for as long as it is being administered. Taken every four hours, night and day, it reduces the risk of opportunistic infection and relieves many neurological complications. However, frequent blood monitoring is required to control anaemia, a potentially life-threatening side effect of AZT. Blood transfusions are often necessary, and the drug must be withdrawn if bone-marrow function is severely affected. Subject by: Russell Webb