In medicine, condition where the body's immune responses are mobilized not against `foreign' matter, such as invading germs, but against the body itself. Diseases considered to be of autoimmune origin include myasthenia gravis, pernicious anaemia, rheumatoid arthritis, and lupus erythematosus. In autoimmune diseases T-lymphocytes reproduce to excess to home in on a target (properly a foriegn disease-causing molecule); however, molecules of the body's own tissue that resemble the target may also be attacked, for example insulin-producing cells, resulting in insulin-dependent diabetes; if certain joint membrane cells are attached, then rheumatoid arthritis may result; and if myelin, the basic protein of the nervous system, then multiple sclerosis. In 1990 in Israel a T-cell vaccine was produced that arrests the excessive reproduction of T-lymphocytes attacking healthy target tissues. Subject by: Russell Webb