Viral infection of the central nervous system affecting nerves that activate muscles. The disease used to be known as infantile paralysis. The World Health Organization expects that polio will be eradicated by 2000. The polio virus is a common one, and mostly, its effects are confined to the throat and intestine, as in flu or a mild digestive upset. There may also be muscle stiffness in the neck and back. Paralysis is seen in about 1% of cases, and the disease is life-threatening only if the muscles of the throat and chest are affected. Cases of this kind, once entombed in an `iron lung', are today maintained on a respirator. Two kinds of vaccine are available, one injected (see Salk) and one given by mouth.