1843-1910. German bacteriologist. Koch and his assistants devised the means to culture bacteria outside the body, and formulated the rules for showing whether or not a bacterium is the cause of a disease. Nobel Prize for Medicine 1905. His techniques enabled him to identify the bacteria responsible for diseases like anthrax, cholera, and tuberculosis. This did not automatically lead to cures, but was crucial in their discovery. Koch was a great teacher, and many of his pupils, such as Kitasato, Ehrlich, and Behring, became outstanding scientists.