1749-1823. English physician who pioneered vaccination. In Jenner's day, smallpox was a major killer. His discovery that inoculation with cowpox gives immunity to smallpox was a great medical breakthrough. He coined the word `vaccination' from the Latin word for cowpox, vaccina. Jenner observed that people who worked with cattle and contracted cowpox from them never subsequently caught smallpox. In 1798 he published his findings that a child inoculated with cowpox, then two months later with smallpox, did not get smallpox.