1712-1770. British Whig politician whose introduction of the the Stamp Act 1765 to raise revenue from the colonies was one of the causes of the American Revolution. Prime minister and chancellor of the Exchequer 1763-65, Grenville took other measures to reduce the military and civil costs in North America, including the Sugar Act and the Quartering Act. His inept management of the Regency Act 1765 damaged his relationship with George III. His government was also responsible for prosecuting the radical John Wilkes.