(3,4-methylenedioxymethamphetamine) illegal drug in increasing use from the 1980s. It is a modified amphetamine with mild psychedelic effects, and works by depleting serotonin (a neurotransmitter) in the brain. Ecstasy was first synthesized 1914 by the Merck pharmaceutical company in Germany, and was one of eight psychedelics tested by the US army 1953, but was otherwise largely forgotten until the mid-1970s. It can be synthesized from nutmeg oil.