1476-1507. Italian general, illegitimate son of Pope Alexander VI. Made a cardinal at 17 by his father, he resigned to become captain-general of the papacy, campaigning successfully against the city republics of Italy. Ruthless and treacherous in war, he was an able ruler (the model for Machiavelli's The Prince), but his power crumbled on the death of his father. He was a patron of artists, including Leonardo da Vinci.