Banting, Frederick Grant 1891-1941. Canadian physician who discovered a technique for isolating the hormone insulin in 1921 when, experimentally, he and his colleague Charles Best tied off the ducts of the pancreas to determine the function of the cells known as the islets of Langerhans. This allowed for the treatment of diabetes. Banting and John J R Macleod, his mentor, shared the 1923 Nobel Prize for Medicine, and Banting divided his prize with Best.