The .45-70 is certainly a record-breaker. It is the oldest cartridge to still be chambered in modern rifles and, along with the .44-40, to still be listed in the factory commercial ammunition tables. In other words, you can still buy it over 120 years after it was introduced! Considerable difference exists in the ability of the older vs. newer .45-70 rifles to handle heavy charges. Handloaders should be mindful to insure that their heavy loads are restricted to arms that are capable. In a modern rifle, the .45-70 is capable of taking any North American game. Bullet weights range from around 300 to 500 grains.